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產(chǎn)品詳情
操作說明
注意事項(xiàng)
中文名稱： 兔抗NFKB2(Phospho-Ser866) 多克隆抗體
英文名稱： Anti-NFKB2(Phospho-Ser866) rabbit polyclonal antibody
別 名： p52; p105; H2TF1; LYT10; CVID10; LYT-10; NF-kB2
抗 原： NFKB2(Phospho-Ser866)
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
反應(yīng)種屬： Human Mouse Rat
相關(guān)類別： 一抗
標(biāo) 記 物： Unconjugate
克隆類型： Unconjugate
技術(shù)規(guī)格
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Background: |
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
NFKB2(Phospho-Ser866) |
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Immunogen: |
Peptide sequence around phosphorylation site of serine 866(E-D-S(p)-A-Y) derived from Human NFκB-p100/p52. |
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Full name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
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Synonyms： |
p52; p105; H2TF1; LYT10; CVID10; LYT-10; NF-kB2 |
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SwissProt: |
Q00653 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
97 kDa |
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WB Positive control: |
Human ovary cancer cells lysate |
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WB Recommended dilution: |
500-1000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
100-200 |
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