Fusion protein corresponding to a region derived from 294-493 amino acids of human DUS2
技術(shù)規(guī)格
Full name:
dihydrouridine synthase 2
Synonyms:
SMM1; DUS2L; URLC8
Swissprot:
Q9NX74
Gene Accession:
BC006527
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene.