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Product Information
Description | Bax rabbit polyclonal |
Protein full name | Apoptosis regulator Bax |
Synonyms | BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bax |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. |
21 kDa |
Observed MW. | 21 kDa |
Uniprot ID | Q07812,Q07813,Q63690 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1:500-1:1000 |
Hela,HepG2,colon cancer,liver cancer |
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Images
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Western blot analysis of Bax (GB11007) at dilution of 1:1000. Lane 1:Hela cell lysate Lane 2:HepG2 cell lysate Lane 3:Human colon cancer lysate Lane 4:Human liver cancer lysate Lane 5:Human breast cancer lysate Lane 6:Human nasopharyngeal cancer tissue lysate Lane 7: KB cell lysate Lane 8:SP20 cell lysate Lane 9:PC12 cell lysate
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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