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Anti -JNK1+JNK2+JNK3 Rabbit pAb

價格: 在線咨詢
貨號:
DRF10157
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC
Species:
M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information



Description

JNK1+JNK2+JNK3 rabbit polyclonal

Protein full name Mitogen-activated protein kinase 8/9/10
Synonyms

JNK1 + JNK2 + JNK3,JNK1/2/3,JNK1+2+3,MAPK8, MAPK9,MAPK10,c Jun N terminal kinase 1,c Jun N terminal kinase 2,c Jun N terminal kinase 3

Immunogen

KLH conjugated Synthetic peptide corresponding to human JNK1

Isotype IgG
Purity Affinity purification

Subcellular location

Cytoplasm, Nucleus
Uniprot ID P45983,P45984,P53779




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1:200-1:800

lung,brain




Background



JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53. JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis.




Images



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Immunohistochemistry analysis of paraffin-embedded mouse lung using JNK1/2/3 (GB11018) at dilution of 1:400


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Immunohistochemistry analysis of paraffin-embedded mouse brain using JNK1/2/3 (GB11018) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded rat brain using JNK1/2/3 (GB11018) at dilution of 1:400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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