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- 手機(jī)：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室
Anti -CollagenI Rabbit pAb
價(jià)格：
在線(xiàn)咨詢(xún)
貨號(hào)：
DRF10160
產(chǎn)品規(guī)格：
100 μL
Applications：
WB/IHC/IF
Species：
H/M/R,H/M/R
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
Collagen I rabbit polyclonal |
|
Protein full name |
Collagen alpha-1(I) chain |
|
Synonyms |
COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse COL1A1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
138 kDa |
|
Observed MW. |
120 kDa |
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
skin, uterus, lung, cartilage |
|
IHC |
Human, Mouse, Rat |
1: 200-1: 1700 |
lung, skin |
|
IF |
Human, Mouse, Rat |
1: 100-1: 1000 |
lung, skin |
Background
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Images
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|
Western blot analysis of Collagen I (GB11022) at dilution of 1: 2000 Lane 1: MCF-7 cell lysate Lane 2: Mouse cartilage tissue lysate Lane 3: Mouse skin tissue lysate Lane 4: Mouse uterus tissue lysate Lane 5: Rat cartilage tissue lysate Lane 6: Rat lung tissue lysate Lane 7: Rat skin tissue lysate
|
|
|
Immunohistochemistry analysis of paraffin-embedded mouse lung using Collagen I (GB11022) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat lung using Collagen I (GB11022) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat skin using Collagen I (GB11022) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p. |
Journal of Experimental & Clinical Cancer Research : CR |
30678736 |
IHC/IF |
|
2 |
P21-activated kinase 1 mediates angiotensin II-induced differentiation of human atrial fibroblasts via the JNK/c-Jun pathway. |
Molecular Medicine Reports |
33495806 |
WB |
|
3 |
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway. |
Journal of Cellular and Molecular Medicine |
31797546 |
WB |
|
4 |
Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway. |
Journal of Cellular and Molecular Medicine |
30953402 |
IHC |
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合肥萬(wàn)物生物科技有限公司
客服熱線(xiàn)：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室