Anti -CollagenI Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF10161

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H/M/R,H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CollagenI rabbit polyclonal
Protein full name	Collagen alpha-1(I) chain
Synonyms	COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse COL1A1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted
Uniprot ID	P11087,P02452,P02454

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse, Rat	1:200-1:2000	bone,pancreas
IF	Human, Mouse, Rat	1:100-1:1000	skin,bone

Background

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

Images

	Immunofluorescence analysis of paraffin-embedded rat skin using CollagenI (GB11022-1) at dilution of 1:200

	Immunohistochemistry analysis of paraffin-embedded mouse bone using CollagenI (GB11022-1) at dilution of 1:2000

	Immunohistochemistry analysis of paraffin-embedded mouse pancreas using CollagenI (GB11022-1) at dilution of 1:2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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