服務(wù)熱線
400-1016-218
聯(lián)系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室
Anti -Histone H3.3 Rabbit pAb
價格：
在線咨詢
貨號：
DRF10165
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
H/M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
Histone H3.3 rabbit polyclonal |
|
Protein full name |
Histone H3.3 |
|
Synonyms |
H3F3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Histone H3.3 |
|
Isotype |
IgG |
|
Predicted MW. |
15 kDa |
|
Observed MW. |
17 kDa |
|
Purity |
Affinity purification |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1:500-1:1000 |
lung, brain |
Background
Histone H3.3 is a protein that in humans is encoded by the H3F3A gene.
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Images
|
Western blot analysis of Histone H3.3 (GB11026) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: MCF-7 cell lysate Lane 4: NIH/3T3 cell lysate Lane 5: RAW 264.7 cell lysate Lane 6: Mouse lung tissue lysate Lane 7: Mouse brain tissue lysate Lane 8: Rat lung tissue lysate Lane 9: Rat brain tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質(zhì)量問題，請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進行質(zhì)檢，確認產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對本公司產(chǎn)品進行驗收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價格范圍之賠償?？蛻粼谑褂眠^程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室