Anti -VEGFA Rabbit pAb

價格：在線咨詢

貨號：

DRF10170

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	VEGFA rabbit polyclona
Protein full name	Vascular endothelial growth factor A
Synonyms	VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse VEGFA
Isotype	IgG
Purity	Affinity purification
Predicted MW.	34-45KDa
Observed MW.	34-45KDa
Subcellular location	Secreted
Uniprot ID	P15692,Q00731,P16612

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1:500-1:1000	B16,liver cancer,kidney

Background

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .

Images

Western blot analysis of VEGF(GB11034) at dilution of 1:1000.

Lane 1:B16 cell lysate

Lane 2:Human nasopharyngeal carcinoma tissue lysate

Lane 3:Human liver cancer tissue lysate

Lane 4:Human liver tissue lysate

Lane 5:Mouse kidney tissue lysate

Lane 6:Mouse brain tissue lysate

Lane 7:Rat kidney tissue lysate

Lane 8:Rat brain tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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