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Anti -Caspase-9 Rabbit pAb

價格: 在線咨詢
貨號:
DRF10175
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Caspase-9 rabbit polyclonal

Protein full name

Caspase-9

Synonyms

CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9

Immunogen

Recombinant protein corresponding to 

Mouse Caspase9 

Isotype

IgG

Purity

Affinity purification

Predicted MW.

50 kDa

Observed MW.

35/46 kDa

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q8C3Q9



Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 800-1: 1000

heart, brain, skeletal muscle



Background


Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increased in the response of cells to genotoxic stress and ABL1/c-Abl activation (By similarity).




Images



圖片 1.png

Western blot analysis of Caspase-9 (GB11053-1) at dilution of 1: 1000

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse skeletal muscle tissue lysate

Lane 3: Mouse brain tissue lysate

Lane 4: Rat heart tissue lysate

Lane 5: Rat skeletal muscle tissue lysate

Lane 6: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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