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Product Information
Description |
CD31 rabbit polyclonal |
Protein full name |
Platelet endothelial cell adhesion molecule |
Synonyms |
CD31 Antigen;EndoCAM; PECAM-1;GPIIA;PECA1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD31 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location |
Cell membrane,Membrane raft,Cell junction |
Uniprot ID | P16284 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human |
1:100-1:1000 |
lung cancer |
IF |
Human |
1:100-1:2000 |
lung cancer |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.
Images
|
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CD31(GB11063-1) at dilution of 1:100 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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