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Product Information
Description |
Choline Acetyltransferase rabbit polyclonal |
Protein full name |
Choline O-acetyltransferase |
Synonyms |
CHAT, CHOACTASE, CMS1A, CMS1A2, CMS6, choline O-acetyltransferase |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CHAT |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location |
Cytoplasm,Cytosol,Nucleus,Presynapse |
Uniprot ID | Q03059,P32738 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1:100-1:500 |
brain |
IF |
Mouse, Rat |
1:100-1:500 |
brain |
Background
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:100 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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