Anti -COX2 / Cyclooxygenase 2 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF10191

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H/M,H/M

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	COX2 rabbit polyclonal
Protein full name	Prostaglandin G/H synthase 2
Synonyms	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse COX2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Microsome membrane, Endoplasmic reticulum membrane
Uniprot ID	Q05769, P35355

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse	1: 500-1: 1000	stomach,colon cancer
IF	Human, Mouse	1: 500-1: 2000	colon cancer, cerebral infarction

Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Images

	Immunohistochemistry analysis of paraffin-embedded human colon cancer using COX2 (GB11077-1) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse stomach using COX2 (GB11077-1) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using COX2 (GB11077-1) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebral infarction using COX2 (GB11077-1) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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