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Anti -Desmin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF10196
產(chǎn)品規(guī)格:
100 μL
Applications:
WB/IHC/IF
Species:
M/R,H/M/R,H/M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Desmin rabbit polyclonal

Protein full name

Desmin

Synonyms

DES, CSM1, CSM2, LGMD2R, desmin

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse desmin
Isotype IgG
Purity Affinity purification
Predicted MW. 54KDa
Observed MW. 55KDa
Subcellular location Cytoplasm,Cell membrane
Uniprot ID P31001,P48675




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000-1: 2000

Heart

IHC

Human, Mouse, Rat

1: 1000-1: 2000

Heart,skeletal muscle

IF

Human, Mouse, Rat

1: 500-1: 2000

Heart,skeletal muscle




Background


Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures . May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.




Images


blob.png

Western blot analysis of Desmin (GB11081) at dilution of 1:1000.

Lane 1:Mouse heart tissue lysate

Lane 2:Mouse heart tissue lysate

Lane 3:Mouse heart tissue lysate

Lane 4:Rat heart tissue lysate

blob.png

Immunohistochemistry analysis of parafffin-embedded mouse heart using Desmin (GB11081) at dilution of 1:1800

blob.png

Immunohistochemistry analysis of parafffin-embedded rat skeletal muscle using Desmin (GB11081) at dilution of 1:1800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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