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Product Information
Description | EGFR rabbit polyclonal |
Protein full name | Epidermal growth factor receptor |
Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse EGFR |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 134KDa |
Observed MW. | 175KDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1:500-1:1000 |
A549,HepG2,MCF7,HCT116 |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
|
Western blot analysis of EGFR (GB11084) at dilution of 1:750. Lane 1:549 cell lysate Lane 2:HepG2 cell lysate Lane 3:MCF7 cell lysate Lane 4:HCT116 cell lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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