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Anti -EGFR Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
DRF10199
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
H
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
| Description | EGFR rabbit polyclonal |
| Protein full name | Epidermal growth factor receptor |
|
Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse EGFR |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 134KDa |
| Observed MW. | 175KDa |
| Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human |
1:600-1:1000 |
HepG2,A549,A431,Hacat,Hct116 |
Background
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules.
Images
|
|
Western blot analysis of EGFR (GB11084-1) at dilution of 1:1000. Lane 1:HepG2 cell lysate Lane 2:A549 cell lysate Lane 3:A431 cell lysate Lane 4:Hacat cell lysate Lane 5:Hct116 cell lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室