服務熱線
400-1016-218
聯(lián)系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室
Anti -EGFR Rabbit pAb
價格：
在線咨詢
貨號：
DRF101100
產品規(guī)格：
100 μL
Applications：
WB
Species：
H/M/R
購買數(shù)量：
產品詳情
操作說明
注意事項
Product Information
| Description | EGFR rabbit polyclonal |
| Protein full name | Epidermal growth factor receptor |
|
Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse EGFR |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 134KDa |
| Observed MW. | 175KDa |
| Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1:500-1:1000 |
HepG2,A549,A431,Hacat,Hct116 |
Background
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules.
Images
|
|
Western blot analysis of EGFR (GB11084-2) at dilution of 1:1000. Lane 1:HepG2 cell lysate Lane 2:A549 cell lysate Lane 3:MCF-7 cell lysate Lane 4:Mouse lung tissue lysate Lane 5:Mouse colon tissue lysate Lane 6:Mouse skin tissue lysate Lane 7:Rat lung tissue lysate Lane 8:Rat colon tissue lysate Lane 9:Rat skin tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥萬物生物科技有限公司銷售的產品均有嚴格的質量保證。如發(fā)現(xiàn)產品存在包裝規(guī)格疑問，請于收貨之日起七日內向我公司總部或當?shù)剞k事處提出，并請保證該產品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質量問題，請于收貨后一月內保留產品50%以上的量，以便本公司回收產品進行質檢，確認產品質量。如逾期，則視為已經對本公司產品進行驗收。 聲明：如發(fā)生產品索賠事宜，本公司僅在產品價格范圍內酌情賠償，恕不接受超出產品價格范圍之賠償?？蛻粼谑褂眠^程中有任何技術問題可以撥打技術售后服務電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室