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Anti -FOXO3A Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101105
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

FOXO3A rabbit polyclonal

Protein full name

Forkhead box protein O3

Synonyms

FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box O3

Immunogen

Recombinant protein corresponding to Mouse FOXO3A

Isotype

IgG

Predicted MW.

71 kDa

Observed MW.

97 kDa

Purity

Affinity purification

Uniprot ID

Q9WVH4, O43524




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1:500-1:1000

liver cancer, glioma, lung, brain




Background


Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.




Images



GB11092-1.png

Western blot analysis of FOXO3A (GB11092-1) at dilution of 1:1000.

Lane 1: 293T cell lysate

Lane 2: MCF7 cell lysate

Lane 3: SH-SY5Y cell lysate

Lane 4 :Human liver cancer tissue lysate

Lane 5: Human glioma tissue lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Mouse brain tissue lysate

Lane 8: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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