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Product Information
Description | FOXP3 rabbit polyclonal |
Protein full name | Forkhead box protein P3 |
Synonyms | FOXP3, AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3 |
Immunogen | Recombinant protein corresponding to Mouse FOXP3 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 47KDa |
Observed MW. | 50KDa |
Uniprot ID | Q99JB6,Q9BZS1 |
Applications
applications | species | dilution | Positive tissue |
WB | Human,Mouse,Rat | 1:500-1:1000 | PC3,inflammatory spleen,thymus gland |
Background
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.
Images
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Western blot analysis of FOXP3 (GB11093-1) at dilution of 1:800. Lane 1:MCF7 cell lysate Lane 2:PC3 cell lysate Lane 3:Mouse inflammatory spleen tissue lysate Lane 4:Mouse thymus gland tissue lysate Lane 5:Mouse spleen tissue lysate Lane 6:Rat thymus gland tissue lysate Lane 7:Rat inflammatory spleen tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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