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Anti -Mesothelin Rabbit pAb

價格: 在線咨詢
貨號:
DRF101131
產品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購買數量:
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產品詳情 操作說明 注意事項

Product Information


Description

Mesothelin rabbit polyclonal

Protein full name

Mesothelin

Synonyms

Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Msln, Mes, CAK1, SMR, SMRP, MAN

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Mesothelin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

49 kDa

Uniprot ID

Q61468, Q9ERA7




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

thymus, heart,

lung, testis




Background


Mesothelin is a glycosyl-phosphatidylinositol-anchored glycoprotein present on the cell surface of various human solid tumors. It is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71kDa precursor protein that is processed to a 40kDa membrane-bound protein termed mesothelin and a 31kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues (e.g. mesothelium), and is expressed at high levels in mesotheliomas, as well as ovarian, pancreatic, and lung cancers. Mesothelin may be a new target for immunotherapy.




Images


image.png

Western blot analysis of Mesothelin (GB111016) at dilution of 1: 1000

Lane 1: Mouse thymus tissue lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Mouse lungs tissue lysate

Lane 4: Rat heart tissue lysate

Lane 5: Rat lung tissue lysate

Lane 6: Rat testis tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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