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Product Information
Description |
Histone H3 rabbit polyclonal |
Protein full name |
Histone H3.1 |
Synonyms |
H3/n, H3/o, H3F2, H3FM, HIST2H3A, HIST2H3C, HIST2H3D, histone cluster 2, H3a, Histone H3, Histone H3.2, Histone H3/m, Histone H3/o, HIST1H3A |
Immunogen |
Recombinant protein corresponding to Mouse Histone H3.1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
15 kDa |
Observed MW. |
17 kDa |
Subcellular location |
Nucleus, Chromosome |
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
WB |
Human, Mouse, Rat |
1: 300-1: 1000 |
liver, spleen |
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Images
|
Western blot analysis of Histone H3.1 (GB11102) at dilution of 1: 500 Lane 1: HeLa cell lysate Lane 2: Jurkat cell lysate Lane 3: RAW 264.7 cell lysate Lane 4: Mouse liver tissue lysate Lane 5: Mouse spleen tissue lysate Lane 6: Rat liver tissue lysate Lane 7: Rat spleen tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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