Anti -GIT1 Rabbit pAb

價格：在線咨詢

貨號：

DRF101138

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	GIT1 rabbit polyclonal
Protein full name	ARF GTPase-activating protein GIT1
Synonyms	ARF GAP GIT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, Git1, Cat1
Immunogen	Recombinant protein corresponding to Mouse GIT1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	85 kDa
Observed MW.	95 kDa
Uniprot ID	Q68FF6, Q9Z272

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	brain

Background

GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes (By similarity). Involved in the regulation of cytokinesis; the function may involve ENTR1 and PTPN13. GIT1 over expression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling.

Images

Western blot analysis of GIT1 (GB111022) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Rat brain tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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