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Product Information
Description |
Fascin rabbit polyclonal |
Protein full name |
Fascin |
Synonyms |
Singed-like protein, Fscn1, Fan1, Snl, HSN, p55, SNL |
Immunogen |
Recombinant protein corresponding to Mouse Fascin |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
55 kDa |
Observed MW. |
55 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, thymus, brain |
Background
Fascin is a highly conserved and ubiquitous actin cross-linking protein that has a major function in cell motility and adhesion. Fascin localizes to a number of highly dynamic cellular structures that require strong mechanical support which include stress fibers and cellular protrusions such as microvilli, microspikes and lamellipodia. Fascin is up-regulated in many human carcinomas. It’s a marker for Reed-Sternberg cells in Hodgkin's disease; it is also a highly selective marker for dendritic cells of lymphoid tissues.
Images
|
Western blot analysis of Fascin (GB111025) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: HepG2 cell lysate Lane 3: A549 cell lysate Lane 4: Mouse spleen tissue lysate Lane 5: Mouse thymus tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat spleen tissue lysate Lane 8: Rat thymus tissue lysate Lane 9: Rat brain tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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