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Product Information
Description |
KAT1 rabbit polyclonal |
Protein full name |
Kynurenine--oxoglutarate transaminase 1 |
Synonyms |
Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Kyat1, Ccbl1, KATI, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase 1, Kat, HAT1, Kynurenine--oxoglutarate transaminase I |
Immunogen |
Recombinant protein corresponding to Mouse KAT1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
48 kDa |
Observed MW. |
48 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
liver, kidney |
Background
This gene encodes a cytosolic enzyme and this protein catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia.
Images
|
Western blot analysis of KAT1 (GB111029) at dilution of 1: 1000 Lane 1: Mouse liver tissue lysate Lane 2: Mouse kidney tissue lysate Lane 3: Rat liver tissue lysate Lane 4: Rat kidney tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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