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Anti -KAT1 / HAT1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101145
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information



Description

KAT1 rabbit polyclonal

Protein full name

Kynurenine--oxoglutarate transaminase 1

Synonyms

Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Kyat1, Ccbl1, KATI, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase 1, Kat, HAT1, Kynurenine--oxoglutarate transaminase I

Immunogen

Recombinant protein corresponding to Mouse KAT1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

48 kDa

Observed MW.

48 kDa

Uniprot ID

Q8BTY1, Q5M939




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

liver, kidney




Background


This gene encodes a cytosolic enzyme and this protein catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia.




Images



image.png

Western blot analysis of KAT1 (GB111029) at dilution of 1: 1000

Lane 1: Mouse liver tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Rat liver tissue lysate

Lane 4: Rat kidney tissue lysate



Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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