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Anti -SIK1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101151
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

SIK1 rabbit polyclonal

Protein full name

Serine/threonine-protein kinase SIK1

Synonyms

HRT-20, Myocardial SNF1-like kinase, Serine/threonine-protein kinase SNF1-like kinase 1, Salt-inducible kinase 1, SIK1

Immunogen

Recombinant protein corresponding to Mouse SIK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

85 kDa

Observed MW.

90 kDa

Uniprot ID

Q60670, Q9R1U5




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

stomach, lung, ovary, heart, ovary




Background


SIK1(Salt-inducible kinase 1) is also named as SIK, SNF1LK and belongs to the CAMK Ser/Thr protein kinase family. It associates constitutively with the NK regulatory complex and is responsible for increases in its catalytic activity following small elevations in intracellular sodium concentrations. SIK1 is required for phosphorylation of class II HDACs and for expression of MEF2 target genes in myocytes. Defects in SIK1 may be associated with some cancers, such as breast cancers. Loss of SIK1 correlates with poor patient outcome in breast cancers.




Images


image.png

Western blot analysis of SIK1 (GB111034) at dilution of 1: 1000

Lane 1: L929 cell lysate

Lane 2: Mouse stomach tissue lysate

Lane 3: Mouse lung tissue lysate

Lane 4: Mouse ovary tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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