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Product Information
Description |
MASPIN rabbit polyclonal |
Protein full name |
Serpin B5 |
Synonyms |
Maspin, Peptidase inhibitor 5, PI-5, Serpinb5, Pi5, Spi5, Spi7, mammary serine proteinase inhibitor, Serpin B |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse MASPIN |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
42 kDa |
Observed MW. |
42 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
colon, uterus, skin |
IHC |
Human, Mouse, Rat |
1: 850-1: 1700 |
colon cancer, colon, skin |
IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
colon cancer, colon, skin |
Background
SERPINB5, also named as PI-5, Maspin and Serpin B5, belongs to the serpin family and Ov-serpin subfamily. It is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, SERPINB5 exhibits no serine protease inhibitory activity.
Images
|
Western blot analysis of MASPIN (GB111040) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: Mouse colon tissue lysate Lane 3: Mouse uterus tissue lysate Lane 4: Mouse skin tissue lysate Lane 5: Rat skin tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded human colon cancer using MASPIN (GB111040) at dilution of 1: 1700 |
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using MASPIN (GB111040) at dilution of 1: 1700 |
|
Immunohistochemistry analysis of paraffin-embedded mouse skin using MASPIN (GB111040) at dilution of 1: 1700 |
|
Immunohistochemistry analysis of paraffin-embedded rat skin using MASPIN (GB111040) at dilution of 1: 1700 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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