Anti -Pannexin 1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101162

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Pannexin 1 rabbit polyclonal
Protein full name	Pannexin-1
Synonyms	Panx1, innexin, MRS1, PX1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Pannexin 1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	48 kDa
Observed MW.	48 kDa
Uniprot ID	Q9JIP4, P60570

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	testis

Background

PANX1, also named as MRS1, belongs to the pannexin family. It plays a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis. It is a structural component of the gap junctions and the hemichannels. PANX1 induced the formation of intercellular channels with characteristics of gap junctions. The PANX1 and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Images

Western blot analysis of Pannexin 1 (GB111044) at dilution of 1: 800

Lane 1: Mouse testis tissue lysate

Lane 2: Rat testis tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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