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Anti -PTPN22 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101164
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

PTPN22 rabbit polyclonal

Protein full name

Tyrosine-protein phosphatase non-receptor type 22

Synonyms

Ptpn22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, PEST-domain phosphatase, PEP, Ptpn8

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PTPN22

Isotype IgG
Purity Affinity purification

Predicted MW.

90 kDa

Observed MW.

110 kDa

Uniprot ID

Q9Y2R2, P29352




Applications


Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

spleen, thymus




Background


This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.




Images


image.png

Western blot analysis of PTPN22 (GB111046) at dilution of 1: 1000

Lane 1: U266 cell lysate

Lane 2: U87 cell lysate

Lane 3: THP-1 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse thymus tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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