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Product Information
Description |
SRF rabbit polyclonal |
Protein full name |
Serum response factor |
Synonyms |
c fos serum response element binding factor, SRF, ERP, MCM1, SAP2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SRF |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1: 1000-1: 3000 |
breast cancer, stomach, ovarian cancer, subcutaneous tumor, small intestine, heart, lung |
IF |
Human, Mouse, Rat |
1: 500-1: 1500 |
breast cancer, stomach, ovarian cancer, subcutaneous tumor, small intestine, heart, lung |
Background
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens and SRF) box super family of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Images
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Immunohistochemistry analysis of paraffin-embedded human breast cancer using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded human stomach using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat small intestine using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse small intestine using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse subcutaneous tumor using SRF (GB111048) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using SRF (GB111048) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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