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Anti -Serum Response Factor SRF Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101166
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H/M/R,H/M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

SRF rabbit polyclonal

Protein full name

Serum response factor

Synonyms

c fos serum response element binding factor, SRF, ERP, MCM1, SAP2

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse SRF

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P11831, Q9JM73, D3ZHH8




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 1000-1: 3000

breast cancer, stomach, ovarian cancer, subcutaneous tumor, small intestine, heart, lung

IF

Human, Mouse, Rat

1: 500-1: 1500

breast cancer, stomach, ovarian cancer, subcutaneous tumor, small intestine, heart, lung




Background


This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens and SRF) box super family of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).




Images


image.png

Immunohistochemistry analysis of paraffin-embedded human breast cancer using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded rat small intestine using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded mouse heart using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded mouse subcutaneous tumor using SRF (GB111048) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using SRF (GB111048) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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