Anti -PTMA Rabbit pAb

價格：在線咨詢

貨號：

DRF101169

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	PTMA rabbit polyclonal
Protein full name	Prothymosin alpha
Synonyms	N-terminally processed, Thymosin alpha, Ptma, Prothymosin alpha like 1 protein
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse PTMA
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	P26350, P06302

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse, Rat	1:750-1:1500	colon, lung
IF	Human, Mouse, Rat	1:500-1:2000	colon, lung

Background

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse colon using PTMA (GB111050) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat lung using PTMA (GB111050) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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