Anti -cIAP2 Rabbit pAb

價格：在線咨詢

貨號：

DRF101170

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

M/R,M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	cIAP2 rabbit polyclonal
Protein full name	Baculoviral IAP repeat-containing protein 3
Synonyms	Cellular inhibitor of apoptosis 2, C-IAP2, Birc3, Inhibitor of apoptosis protein 1, mIAP1, RING-type E3 ubiquitin transferase BIRC3
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse cIAP2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Predicted MW.	67 kDa
Observed MW.	67 kDa
Uniprot ID	O08863, Q5XIW4

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	thymus, testes, lymph nodes
IHC	Mouse, Rat	1: 1500-1: 3000	lung, testis, spleen
IF	Mouse, Rat	1: 750-1: 1500	lung, testis, spleen

Background

Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.

Images

	Western blot analysis of cIAP2 (GB111051) at dilution of 1: 750 Lane 1: Mouse thymus tissue lysate Lane 2: Mouse lymph nodes tissue lysate Lane 3: Mouse testes tissue lysate Lane 4: Rat thymus tissue lysate
	Immunohistochemistry analysis of paraffin-embedded mouse lung using cIAP2 (GB111051) at dilution of 1: 3000
	Immunohistochemistry analysis of paraffin-embedded mouse testis using cIAP2 (GB111051) at dilution of 1: 3000
	Immunohistochemistry analysis of paraffin-embedded mouse spleen using cIAP2 (GB111051) at dilution of 1: 3000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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