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Anti -5HT1A Receptor Rabbit pAb

價格: 在線咨詢
貨號:
DRF101181
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

5HT1A Receptor rabbit polyclonal

Protein full name

5-hydroxytryptamine receptor 1A

Synonyms

5-HT-1A, G-21, Serotonin receptor 1A, HTR1A, ADRB2RL1, ADRBRL1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse 5HT1A Receptor

Isotype

IgG

Purity

Affinity purification

Predicted MW.

46 kDa

Observed MW.

46 kDa

Uniprot ID

P08908




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Jurkat, Caco2, Raji, HepG2, HCT116




Background


G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.




Images


Western blot analysis of 5HT1A Receptor (GB111060) at dilution of 1: 1000
Lane 1: Jurkat cell lysate
Lane 2: Caco2 cell lysate
Lane 3: Raji cell lysate
Lane 4: HepG2 cell lysate
Lane 5: HCT116 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.


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