服務熱線
400-1016-218
全國統(tǒng)一服務熱線
400-1016-218
科研好幫手 專業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁 > 產(chǎn)品中心 > 抗體 >>一抗 >>多克隆抗體 >> Anti -5HT1A Receptor Rabbit pAb
Product Information
Description |
5HT1A Receptor rabbit polyclonal |
Protein full name |
5-hydroxytryptamine receptor 1A |
Synonyms |
5-HT-1A, G-21, Serotonin receptor 1A, HTR1A, ADRB2RL1, ADRBRL1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse 5HT1A Receptor |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
46 kDa |
Observed MW. |
46 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 500-1: 1000 |
Jurkat, Caco2, Raji, HepG2, HCT116 |
Background
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Images
Western blot analysis of 5HT1A Receptor (GB111060) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
合肥萬物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室