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Product Information
Description |
CAMK2B rabbit polyclonal |
Protein full name |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
Synonyms |
CaM kinase II subunit beta, CaMK-II subunit beta, Camk2b, Camk2d |
Immunogen |
Recombinant protein corresponding to Mouse CAMK2B |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
60 kDa |
Observed MW. |
60 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 300-1: 600 |
HeLa, SH-SY5Y, U251, N2A, PC12 |
Background
CaMKII beta (Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAMK2B, CAM2 or CAMKB, belongs to the protein kinase super family, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a member of the NMDAR signaling complex in excitatory synapses, it may functions autonomously after Ca2+ calmodulin binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.
Images
Western blot analysis of CAMK2B (GB111070) at dilution of 1: 600 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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