Anti -CD81 Rabbit pAb

價(jià)格：在線咨詢

貨號：

DRF101195

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD81 rabbit polyclonal
Protein full name	CD81 antigen
Synonyms	26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, CD81, Tapa1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD81
Isotype	IgG
Purity	Affinity purification
Predicted MW.	26 kDa
Observed MW.	30 kDa
Uniprot ID	P60033, P35762, Q62745

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	skeletal muscle

Background

CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 appears to promote muscle cell fusion and support myotube maintenance. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Images

Western blot analysis of CD81 (GB111073)

at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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