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Anti -WDR59 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101245
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

WDR59 rabbit polyclonal

Protein full name

GATOR complex protein WDR59

Synonyms

CUL4- and DDB1-associated WDR protein 12, WD repeat-containing protein 59, Wdr59, Cdw12

Immunogen

Recombinant protein corresponding to Mouse WDR59

Isotype

IgG

Purity

Affinity purification

Predicted MW.

112 kDa

Observed MW.

112 kDa

Uniprot ID

Q8C0M0




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, muscle




Background


As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.




Images


Western blot analysis of WDR59 (GB111121) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse muscle tissue lysate
Lane 3: Rat brain tissue lysate
Lane 4: Rat muscle tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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