Anti -ATG3 Rabbit pAb

價格：在線咨詢

貨號：

DRF101255

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H/M

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	ATG3 rabbit polyclonal
Protein full name	Ubiquitin-like-conjugating enzyme ATG3
Synonyms	Autophagy-related protein 3, Protein PC3-96, APG3-like, hApg3, ATG3, APG3, APG3L
Immunogen	Recombinant protein corresponding to Human ATG3
Isotype	IgG
Purity	Affinity purification
Predicted MW.	36 kDa
Observed MW.	40 kDa
Uniprot ID	Q9NT62, Q9CPX6

Applications

Applications

Species

Dilution

Positive Tissue

Human, Mouse

1: 500-1: 1000

THP-2, A20,

HeLa, Jurkat

Background

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

Images

Western blot analysis of ATG3 (GB111131) at dilution of 1: 1000
Lane 1: THP-2 cell lysate
Lane 2: A20 cell lysate
Lane 3: Hela cell lysate
Lane 4: Jurkat cell lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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