Anti -Lipocalin-2 / NGAL Rabbit pAb

價格：在線咨詢

貨號：

DRF101258

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	NGAL rabbit polyclonal
Protein full name	Neutrophil gelatinase-associated lipocalin
Synonyms	NGAL, Lipocalin-2, Oncogene 24p3, Siderocalin, p25
Immunogen	Recombinant protein corresponding to Human NGAL
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted
Uniprot ID	P80188

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 500-1: 2000	lung, lung cancer, liver cancer
IF	Human	1: 500-1: 3000	colon

Background

Lipocalin 2 is a member of the lipocalin family, It involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Images

	Immunohistochemistry analysis of paraffin-embedded human lung using NGAL (GB111134) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded human lung cancer using NGAL (GB111134) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded human liver cancer using NGAL (GB111134) at dilution of 1: 1000
	Immunofluorescent analysis of paraffin-embedded human colon using NGAL (GB111134) at dilution of 1:1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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