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Anti -ATF-4 Rabbit pAb

價(jià)格: 在線咨詢(xún)
貨號(hào):
DRF101261
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H/M/R,H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

ATF-4 rabbit polyclonal

Protein full name

Cyclic AMP-dependent transcription factor ATF-4

Synonyms

cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4

Immunogen

Recombinant protein corresponding to Mouse ATF-4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm, Nucleus

Uniprot ID

P18848, Q06507, Q9ES19




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 1500-1: 3000

colon, liver, brain,  small intestine, kidney

IF

Human, Mouse, Rat

1: 1500-1: 3000

breast, liver, brain




Background



This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.




Images


Immunohistochemistry analysis of paraffin-embedded human colon using ATF-4 (GB111137) at dilution of 1: 1600

Immunohistochemistry analysis of paraffin-embedded mouse colon using ATF-4 (GB111137) at dilution of 1: 1600

Immunohistochemistry analysis of paraffin-embedded mouse brain using ATF-4 (GB111137) at dilution of 1: 1600

Immunohistochemistry analysis of paraffin-embedded mouse liver using ATF-4 (GB111137) at dilution of 1: 1600

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using ATF-4 (GB111137) at dilution of 1: 1600

Immunohistochemistry analysis of paraffin-embedded rat kidney using ATF-4 (GB111137) at dilution of 1: 1600

Immunofluorescent analysis of paraffin-embedded human breast using ATF-4 (GB111137) at dilution of 1: 1500

Immunofluorescent analysis of paraffin-embedded mouse liver using ATF-4 (GB111137) at dilution of 1: 1500

Immunofluorescent analysis of paraffin-embedded rat brain using ATF-4 (GB111137) at dilution of 1: 1500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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