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Product Information
Description |
S100A9 rabbit polyclonal |
Protein full name |
Protein S100-A9 |
Synonyms |
Calgranulin-B, Leukocyte L1 complex heavy chain, MRP-14, p14, S100 calcium-binding protein A9, S100a9, Cagb, Mrp14 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100A9 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
13 kDa |
Observed MW. |
13 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 300-1: 800 |
spleen, lung |
IHC |
Mouse, Rat |
1: 1500-1: 3000 |
lung, liver, spleen, small intestine |
IF |
Mouse, Rat |
1: 750-1: 1500 |
lung, spleen |
Background
Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
Images
Western blot analysis of S100A9 (GB111149) at dilution of 1: 800 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded rat liver using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded rat small intestine using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunofluorescent analysis of paraffin-embedded mouse lung using S100A9 (GB111149) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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