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Product Information
Description |
ATF-4 rabbit polyclonal |
Protein full name |
Cyclic AMP-dependent transcription factor ATF-4 |
Synonyms |
cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4 |
Immunogen |
Recombinant protein corresponding to Mouse ATF-4 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
38 kDa |
Observed MW. |
45 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
marrow, brain, cortex |
Background
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Images
Western blot analysis of ATF-4 (GB111157) at dilution of 1: 1000 Lane 1: Mouse marrow tissue lysate Lane 2: Rat brain tissue lysate Lane 3: Rat cortex tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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