Anti -Villin Mouse mAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101341

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

H,M,R | H,M,R | H,M,R

品牌：

萬物

購(gòu)買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Villin mouse molyclonal
Protein full name	Villin-1
Synonyms	VIL1, VIL, Villin 1, D2S1471
Immunogen	Recombinant protein corresponding to Mouse Villin
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	93 kDa
Observed MW.	95 kDa
Uniprot ID	P09327, Q62468

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	small intestine, kidney, colon
IHC	Human, Mouse, Rat	1: 500-1: 2000	small intestine, jejunum
IF	Human, Mouse, Rat	1: 500-1: 1000

Background

Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma.

Images

	Western blot analysis of Villin (GB121209) at dilution of 1: 1000 Lane 1: CaCO2 cell lysate Lane 2: Mouse small intestine tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Mouse colon tissue lysate Lane 5: Rat small intestine tissue lysate Lane 6: Rat kidney tissue lysate Lane 7: Rat colon tissue lysate
	Immunohistochemistry analysis of paraffin-embedded human small intestine using Villin (GB121209) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse jejunum using Villin (GB121209) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat jejunum using Villin (GB121209) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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