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Anti -CD73 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101947
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

CD73 rabbit polyclonal

Protein full name

5'-nucleotidase

Synonyms

5'-NT, CD73, Nt5e, Nt5, Nte, 5' nucleotidase precursor, E5NT, Ecto-5'-nucleotidase

Immunogen

Recombinant protein corresponding to Mouse CD73

Isotype

IgG

Purity

Affinity purification

Predicted MW.

64 kDa

Observed MW.

64 kDa

Uniprot ID

P21589, Q61503, P21588




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, kidney, retina




Background


CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts.




Images


圖片 1.png

Western blot analysis of CD73 (GB111807)

at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse kidney tissue lysate

Lane 4: Rat liver tissue lysate

Lane 5: Rat kidney tissue lysate

Lane 6: Rat retina tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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