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Anti -Choline Acetyltransferase Rabbit pAb

價格: 在線咨詢
貨號:
KT011452
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC、IF
Species:
M,R | M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information



Description

Choline Acetyltransferase rabbit polyclonal

Protein full name

Choline O-acetyltransferase

Synonyms

CHAT, CHOACTASE, CMS1A, CMS1A2, CMS6, choline O-acetyltransferase

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CHAT

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm,Cytosol,Nucleus,Presynapse

Uniprot ID Q03059,P32738




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1:100-1:500

brain

IF

Mouse, Rat

1:100-1:500

brain




Background



This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.




Images



blob.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:500

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using ChAT(GB11070) at dilution of 1:100




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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