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Product Information
Description |
5HT2A Receptor rabbit polyclonal |
Protein full name |
5-hydroxytryptamine receptor 2A |
Synonyms |
5-HT-2, 5-HT-2A, Serotonin receptor 2A, Htr2a, Htr2, serotonin 5-HT-2 receptor, 5 hydroxytryptamine receptor 2A |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse 5HT2A |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
53 kDa |
Observed MW. |
53 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
cerebral cortex, brain, colon, cerebellum |
IHC |
Human, Mouse, Rat |
1: 200-1: 800 |
colon cancer, small intestine |
IF |
Human, Mouse, Rat |
1: 100-1: 2000 |
colon cancer, small intestine |
Background
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Images
|
Western blot analysis of 5HT2A (GB111001) at dilution of 1: 1000 Lane 1: Mouse cerebral cortex tissue lysate Lane 2: Mouse brain tissue lysate Lane 3: Mouse colon tissue lysate Lane 4: Mouse cerebellum tissue lysate Lane 5: Rat cerebral cortex tissue lysate Lane 6: Rat brain tissue lysate Lane 7: Rat colon tissue lysate Lane 8: Rat cerebellum tissue lysate
|
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Immunohistochemistry analysis of paraffin-embedded Human colon cancer using 5HT2A (GB111001) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded mouse small intestine using 5HT2A (GB111001) at dilution of 1: 400 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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