Anti -5HT1A Receptor Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011456

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	5HT1A Receptor rabbit polyclonal antibody
Protein full name	5-hydroxytryptamine receptor 1A
Synonyms	5-HT-1A, G-21, Serotonin receptor 1A, HTR1A, ADRB2RL1, ADRBRL1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse 5HT1A Receptor
Isotype	IgG
Purity	Affinity purification
Predicted MW.	46 kDa
Observed MW.	46 kDa
Uniprot ID	P08908

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human	1: 500-1: 1000	Jurkat, CACO-2, Raji, HepG2, HCT116

Background

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Images

Picture 1.png

Western blot analysis of 5-HT1A (GB111060) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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