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Product Information
Description |
HOMER3 rabbit polyclonal |
Protein full name |
Homer protein homolog 3 |
Synonyms |
Homer-3, HOMER 3, homer homolog 3 (Drosophila), VESL3, Homer 3D protein |
Immunogen |
Recombinant protein corresponding to Mouse HOMER3 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
40 kDa |
Observed MW. |
40 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 1000-1: 2000 |
brain, cerebellum, spleen, lung |
IHC |
Mouse, Rat |
1: 700-1: 2000 |
cerebellum, spleen, placenta |
IF |
Mouse, Rat |
1: 700-1: 2100 |
cerebellum, spleen, placenta |
Background
HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.
Images
|
Western blot analysis of HOMER3 (GB111825) at dilution of 1: 2000 Lane 1: Mouse brain tissue lysate Lane 2: Mouse cerebellumX tissue lysate Lane 3: Mouse lung tissue lysate Lane 4: Rat brain tissue lysate Lane 5: Rat cerebellum tissue lysate Lane 6: Rat spleen tissue lysate Lane 7: Rat lung tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using HOMER3 (GB111825) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat cerebellum using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat placenta using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebellum using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat cerebellum using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using HOMER3 (GB111825) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat placenta using HOMER3 (GB111825) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬物生物科技有限公司
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