Recombinant protein corresponding to Mouse 5HT6 Receptor
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cell membrane
Predicted MW.
47 kDa
Observed MW.
47 kDa
Uniprot ID
P50406, Q9R1C8, P31388
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 500-1: 1000
brain, cerebral cortex
IHC/IF
Mouse, Rat
1: 600-1: 1200
corpus striatum, prefrontal lobe
Background
This
gene encodes a protein that belongs to the seven-transmembrane G
protein-coupled receptor family of proteins. The encoded protein couples
with the Gs alpha subunit and stimulates adenylate cyclase to activate
the cyclic AMP-dependent signaling pathway. This receptor is thought to
regulate cholinergic neuronal transmission in the brain. Several
antidepressants and antipsychotic drugs have a high affinity for this
receptor.
Images
Western blot analysis of 5HT6 (GB112416) at dilution of 1: 500
Immunofluorescence of paraffin embedded mouse prefrontal lobe using 5HT6 (GB112416) at dilution of 1: 600 (400x lens)
Immunofluorescence of paraffin embedded rat corpus striatum using 5HT6 (GB112416) at dilution of 1: 600 (250x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .