Anti -GPX1 Rabbit pAb

價格：在線咨詢

貨號：

KT011481

產(chǎn)品規(guī)格：

Applications：

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	GPX1 rabbit polyclonal antibody
Protein full name	Glutathione peroxidase 1
Synonyms	GPX1, GPXD, GSHPX1, glutathione peroxidase 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse GPX1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	22 kDa
Observed MW.	22 kDa
Uniprot ID	P11352, P04041

Applications

applications	species	dilution	Positive tissue
WB	Mouse, Rat	1: 500-1: 1000	liver, spleen, kidney

Background

As a glutathione peroxidase, GPx1 functions in the detoxification of hydrogen peroxide, specifically by catalyzing the reduction of hydrogen peroxide to water. The glutathione peroxidase also catalyzes the reduction of other organic hydroperoxides, such as lipidperoxides, to the corresponding alcohols.GPx1 typically uses glutathione (GSH) as the reductant, but when glutathione synthetase (GSS) is, as in brain mitochondria, γ-glutamylcysteine can serve as the reductant instead.The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress.This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.

Images

Picture 1.png

Western blot analysis of GPX1 (GB11291) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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