Anti -Nicotinic Acetylcholine Receptor beta/CHRNB1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011484

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC

Species：

M,R

品牌：

萬(wàn)物

購(gòu)買數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	Nicotinic Acetylcholine Receptor beta/CHRNB1 rabbit polyclonal
Protein full name	Acetylcholine receptor subunit beta
Synonyms	ACHRB, CHRNB, CHRNB1, CMS1D, CMS2A, SCCMS, Nicotinic acetylcholine receptor beta subunit precursor
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Nicotinic Acetylcholine Receptor beta/CHRNB1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	P09690, P25109

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 1000-1: 2000	cerebellum

Background

Acetylcholine receptors (AChRs) are integral membrane proteins that respond to the binding of acetylcholine (ACh), a neurotransmitter synthesized, stored and finally released by cholinergic neurons. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) subunits. CHRNB1 gene encodes acetylcholine receptor subunit beta (ACHRB). Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Images

圖片 1.png

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using

Chrnb1 (GB113337) at dilution of 1: 2000

圖片 2.png

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using

Chrnb1 (GB113337) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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