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Product Information
Description |
GABA A Receptor beta 3/GABRB3 rabbit polyclonal |
Protein full name |
Gamma-aminobutyric acid receptor subunit beta-3 |
Synonyms |
GABA(A) receptor subunit beta-3, Gabrb3, Gabrb-3, ECA5, GABA alpha receptor beta-2 subunit |
Immunogen |
Recombinant protein corresponding to Mouse GABRB3 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
54 kDa |
Observed MW. |
54 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 800 |
cerebral cortex, brain |
Background
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Images
Western blot analysis of GABRB3 (GB113513) at dilution of 1: 800 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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