Anti -Neurofilament heavy polypeptide Mouse mAb

價格：在線咨詢

貨號：

KT011606

產品規(guī)格：

100ul

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	Neurofilament heavy polypeptide mouse monoclonal
Protein full name	Neurofilament heavy polypeptide
Synonyms	NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, Nefh, Kiaa0845, Nfh, NF200, NF
Immunogen	Recombinant protein corresponding to Mouse NF200
Isotype	IgG2a
Purity	Affinity purification
Predicted MW.	117 kDa
Observed MW.	200 kDa
Uniprot ID	P19246

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 1000-1: 2000	brain, hippocampus, cerebellum

Background

NEFH (NF200), also named as KIAA0845 and NFH, belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10 nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody can recognize both NEFH and NEFM.

Images

Western blot analysis of NF200 (GB12141)

at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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